Prescription Medication and Migraine Relief
New therapies to treat headache go back to the beginning of the last century when ergotamine tartrate was first isolated in a laboratory. It was this development which introduced clinical practice into treating migraines. Ergotamine works by constricting blood vessels in the head. About twenty-five years later researchers began to suspect that disturbances in the brain’s serotonin level played a role in migraine. The drug, methysergide, a serotonin antagonist that prevents migraine attacks, was introduced into clinical practice in 1958. In recent years, new technologies have made it possible for researchers to identify serotonin receptors throughout the body. It is now believed that serotonin levels actually decrease at the onset of a migraine attack, causing blood vessels to dilate and surrounding tissues to swell. This is that brings on the pain.
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Topic: Migraine Information
